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KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners
Regulatory T cells (Tregs) are indispensable for the establishment of tolerance of self-antigens in animals. The transcriptional regulator Foxp3 is critical for Treg development and function, controlling the expression of genes important for Tregs through interactions with binding partners. We previ...
Autores principales: | Tanaka, Shigeru, Pfleger, Christian, Lai, Jen-Feng, Roan, Florence, Sun, Shao-Cong, Ziegler, Steven F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947873/ https://www.ncbi.nlm.nih.gov/pubmed/29669285 http://dx.doi.org/10.1016/j.celrep.2018.03.099 |
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