Cargando…

Spherical-supported membranes as platforms for screening against membrane protein targets

Screening assays performed against membrane protein targets (e.g. phage display) are hampered by issues arising from protein expression and purification, protein stability in detergent solutions and epitope concealment by detergent micelles. Here, we have studied a fast and simple method to improve...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasilca, V., Sadeghpour, A., Rawson, S., Hawke, L.E., Baldwin, S.A., Wilkinson, T., Bannister, D., Postis, V.L.G., Rappolt, M., Muench, S.P., Jeuken, L.J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948183/
https://www.ncbi.nlm.nih.gov/pubmed/29545094
http://dx.doi.org/10.1016/j.ab.2018.03.006