Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation

It is critical to understand the molecular mechanisms of hepatocarcinogenesis in order to prevent or treat hepatocellular carcinoma (HCC). The development of HCC is commonly associated with hepatocyte death and compensatory proliferation. However, the role of Caspase-3, a key apoptotic executor, in...

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Detalles Bibliográficos
Autores principales: Shang, Na, Bank, Thomas, Ding, Xianzhong, Breslin, Peter, Li, Jun, Shi, Baomin, Qiu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948202/
https://www.ncbi.nlm.nih.gov/pubmed/29752472
http://dx.doi.org/10.1038/s41419-018-0617-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948202/
https://www.ncbi.nlm.nih.gov/pubmed/29752472
http://dx.doi.org/10.1038/s41419-018-0617-7

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