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Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation
It is critical to understand the molecular mechanisms of hepatocarcinogenesis in order to prevent or treat hepatocellular carcinoma (HCC). The development of HCC is commonly associated with hepatocyte death and compensatory proliferation. However, the role of Caspase-3, a key apoptotic executor, in...
Autores principales: | Shang, Na, Bank, Thomas, Ding, Xianzhong, Breslin, Peter, Li, Jun, Shi, Baomin, Qiu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948202/ https://www.ncbi.nlm.nih.gov/pubmed/29752472 http://dx.doi.org/10.1038/s41419-018-0617-7 |
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