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Checkpoint suppressor 1 suppresses transcriptional activity of ERα and breast cancer cell proliferation via deacetylase SIRT1

Breast cancer is a highly heterogeneous carcinoma in women worldwide, but the underlying mechanisms that account for breast cancer initiation and development have not been fully established. Mounting evidence indicates that Checkpoint suppressor 1 (CHES1) is tightly associated with tumorigenesis and...

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Detalles Bibliográficos
Autores principales: Xu, Zhaowei, Yang, Yangyang, Li, Bowen, Li, Yanan, Xia, Kangkai, Yang, Yuxi, Li, Xiahui, Wang, Miao, Li, Shujing, Wu, Huijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948204/
https://www.ncbi.nlm.nih.gov/pubmed/29752474
http://dx.doi.org/10.1038/s41419-018-0629-3