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Activation of TGF-β-activated kinase 1 (TAK1) restricts Salmonella Typhimurium growth by inducing AMPK activation and autophagy

Autophagy is a conserved cellular process that functions as a first-line defense to restrict the growth of invading parasitic bacteria. As an intracellular pathogen, Salmonella (S) Typhimurium invades host cells through two Type III secretion systems (T3SS) and resides in the Salmonella-containing v...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Jiang, Yuanyuan, Sun, Jing, Geng, Shizhong, Pan, Zhiming, Prinz, Richard A., Wang, Chengming, Sun, Jun, Jiao, Xinan, Xu, Xiulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948208/
https://www.ncbi.nlm.nih.gov/pubmed/29752434
http://dx.doi.org/10.1038/s41419-018-0612-z