Targeting MUC1-C suppresses BCL2A1 in triple-negative breast cancer

B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs; however, there are presently no agents that target BCL2A1. The MUC1-C oncoprotein is aberrantly expressed in triple-negative breast ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Hiraki, Masayuki, Maeda, Takahiro, Mehrotra, Neha, Jin, Caining, Alam, Maroof, Bouillez, Audrey, Hata, Tsuyoshi, Tagde, Ashujit, Keating, Amy, Kharbanda, Surender, Singh, Harpal, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948210/
https://www.ncbi.nlm.nih.gov/pubmed/29760958
http://dx.doi.org/10.1038/s41392-018-0013-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948210/
https://www.ncbi.nlm.nih.gov/pubmed/29760958
http://dx.doi.org/10.1038/s41392-018-0013-x

Ejemplares similares