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Cre Recombinase Mediates the Removal of Bacterial Backbone to Efficiently Generate rSV40
Gene therapy has been shown to be a feasible approach to treat inherited disorders in vivo. Among the currently used viral vector systems, adeno-associated virus (AAV) vectors are the most advanced and have been applied in patients successfully. An important drawback of non-integrating AAV vectors i...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948228/ https://www.ncbi.nlm.nih.gov/pubmed/29766030 http://dx.doi.org/10.1016/j.omtm.2018.02.010 |