Cre Recombinase Mediates the Removal of Bacterial Backbone to Efficiently Generate rSV40

Gene therapy has been shown to be a feasible approach to treat inherited disorders in vivo. Among the currently used viral vector systems, adeno-associated virus (AAV) vectors are the most advanced and have been applied in patients successfully. An important drawback of non-integrating AAV vectors i...

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Detalles Bibliográficos
Autores principales: Shi, Xiaoxia, Ykema, Matthew Ryan, Hazenoot, Jaco, ten Bloemendaal, Lysbeth, Mancini, Irene, Odijk, Machteld, de Haan, Peter, Bosma, Piter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948228/
https://www.ncbi.nlm.nih.gov/pubmed/29766030
http://dx.doi.org/10.1016/j.omtm.2018.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948228/
https://www.ncbi.nlm.nih.gov/pubmed/29766030
http://dx.doi.org/10.1016/j.omtm.2018.02.010

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