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Catechol-O-Methyltransferase Val158Met Polymorphism on Striatum Structural Covariance Networks in Alzheimer’s Disease

The catechol-O-methyltransferase enzyme metabolizes dopamine in the prefrontal axis, and its genetic polymorphism (rs4680; Val158Met) is a known determinant of dopamine signaling. In this study, we investigated the possible structural covariance networks that may be modulated by this functional poly...

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Detalles Bibliográficos
Autores principales: Chang, Chiung-Chih, Tsai, Shih-Jen, Chen, Nai-Ching, Huang, Chi-Wei, Hsu, Shih-Wei, Chang, Ya-Ting, Liu, Mu-En, Chang, Wen-Neng, Tsai, Wan-Chen, Lee, Chen-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948254/
https://www.ncbi.nlm.nih.gov/pubmed/28707072
http://dx.doi.org/10.1007/s12035-017-0668-2