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Natural compound sanguinarine chloride targets the type III secretion system of Salmonella enterica Serovar Typhimurium

The type III secretion system (T3SS) is a key virulence mechanism of many Gram-negative bacterial pathogens. Upon contact between bacteria and host cells, T3SS transfers a series of effectors from the bacterial cytosol to host cells. It is widely known that a mutation in T3SS does not impair bacteri...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Liu, Yan, Wang, Tingting, Deng, Xuming, Chu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948472/
https://www.ncbi.nlm.nih.gov/pubmed/29761161
http://dx.doi.org/10.1016/j.bbrep.2018.04.011