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Engineering a vitamin B(12) high-throughput screening system by riboswitch sensor in Sinorhizobium meliloti

BACKGROUND: As a very important coenzyme in the cell metabolism, Vitamin B(12) (cobalamin, VB(12)) has been widely used in food and medicine fields. The complete biosynthesis of VB(12) requires approximately 30 genes, but overexpression of these genes did not result in expected increase of VB(12) pr...

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Detalles Bibliográficos
Autores principales: Cai, Yingying, Xia, Miaomiao, Dong, Huina, Qian, Yuan, Zhang, Tongcun, Zhu, Beiwei, Wu, Jinchuan, Zhang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948670/
https://www.ncbi.nlm.nih.gov/pubmed/29751749
http://dx.doi.org/10.1186/s12896-018-0441-2