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Engineering a vitamin B(12) high-throughput screening system by riboswitch sensor in Sinorhizobium meliloti
BACKGROUND: As a very important coenzyme in the cell metabolism, Vitamin B(12) (cobalamin, VB(12)) has been widely used in food and medicine fields. The complete biosynthesis of VB(12) requires approximately 30 genes, but overexpression of these genes did not result in expected increase of VB(12) pr...
Autores principales: | Cai, Yingying, Xia, Miaomiao, Dong, Huina, Qian, Yuan, Zhang, Tongcun, Zhu, Beiwei, Wu, Jinchuan, Zhang, Dawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948670/ https://www.ncbi.nlm.nih.gov/pubmed/29751749 http://dx.doi.org/10.1186/s12896-018-0441-2 |
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