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Changes in phenotype and differentiation potential of human mesenchymal stem cells aging in vitro

BACKGROUND: Adult mesenchymal stem cells (MSCs) hold great promise for regenerative medicine because of their self-renewal, multipotency, and trophic and immunosuppressive effects. Due to the rareness and high heterogeneity of freshly isolated MSCs, extensive in-vitro passage is required to expand t...

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Detalles Bibliográficos
Autores principales: Yang, Yueh-Hsun Kevin, Ogando, Courtney R., Wang See, Carmine, Chang, Tsui-Yun, Barabino, Gilda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948736/
https://www.ncbi.nlm.nih.gov/pubmed/29751774
http://dx.doi.org/10.1186/s13287-018-0876-3