Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterized by selective degeneration of dopaminergic (DA) neurons of the substantia nigra pars compacta (SN) while neighboring ventral tegmental area (VTA) DA neurons are relatively spared. Mechanisms underlying the selective protection of the VTA and susce...

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Detalles Bibliográficos
Autores principales: Kostuk, Eric Wildon, Cai, Jingli, Iacovitti, Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948771/
https://www.ncbi.nlm.nih.gov/pubmed/29751760
http://dx.doi.org/10.1186/s12974-018-1181-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948771/
https://www.ncbi.nlm.nih.gov/pubmed/29751760
http://dx.doi.org/10.1186/s12974-018-1181-x

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