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Systemically administered allogeneic mesenchymal stem cells do not aggravate the progression of precancerous lesions: a new biosafety insight

BACKGROUND: Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal cells currently tested for multiple therapeutic purposes. Their potential to home into tumors, to secrete trophic/vasculogenic factors, and to suppress immune response raises questions regarding their biosafety. Our aim...

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Detalles Bibliográficos
Autores principales: Bruna, Flavia, Plaza, Anita, Arango, Martha, Espinoza, Iris, Conget, Paulette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948822/
https://www.ncbi.nlm.nih.gov/pubmed/29751770
http://dx.doi.org/10.1186/s13287-018-0878-1