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Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity

BACKGROUND: The activity of cerebrospinal fluid (CSF) β-site APP cleaving enzyme (BACE) is a potential diagnostic biomarker for Alzheimer disease (AD). METHODS: A total of 340 non-Hispanic Caucasian participants from the Alzheimer’s Disease Neuroimaging Initiative cohort (ADNI) database were include...

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Detalles Bibliográficos
Autores principales: Hu, Hao, Li, Haiyan, Li, Jieqiong, Yu, Jintai, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948839/
https://www.ncbi.nlm.nih.gov/pubmed/29751835
http://dx.doi.org/10.1186/s12881-018-0603-z