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Physical interaction of STAT1 isoforms with TGF-β receptors leads to functional crosstalk between two signaling pathways in epithelial ovarian cancer

BACKGROUND: The signal transducer and activator of transcription (STAT) and transforming growth factor-β (TGF-β) signaling pathways play important roles in epithelial ovarian cancer (EOC). However, the mechanism of crosstalk between two pathways is not completely understood. METHODS: The expression...

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Detalles Bibliográficos
Autores principales: Tian, Xiaoling, Guan, Wencai, Zhang, Lingyun, Sun, Wenwen, Zhou, Daibing, Lin, Qunbo, Ren, Weimin, Nadeem, Lubna, Xu, Guoxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948853/
https://www.ncbi.nlm.nih.gov/pubmed/29751820
http://dx.doi.org/10.1186/s13046-018-0773-8