Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart

BACKGROUND: Epidemiological studies show that maternal diabetes predisposes offspring to cardiovascular and metabolic disorders. However, the precise mechanisms for the underlying penetrance and disease predisposition remain poorly understood. We examined whether hypoxia-inducible factor 1 alpha, in...

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Detalles Bibliográficos
Autores principales: Cerychova, Radka, Bohuslavova, Romana, Papousek, Frantisek, Sedmera, David, Abaffy, Pavel, Benes, Vladimir, Kolar, Frantisek, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948854/
https://www.ncbi.nlm.nih.gov/pubmed/29753320
http://dx.doi.org/10.1186/s12933-018-0713-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948854/
https://www.ncbi.nlm.nih.gov/pubmed/29753320
http://dx.doi.org/10.1186/s12933-018-0713-0

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