Cargando…
Adverse effects of Hif1a mutation and maternal diabetes on the offspring heart
BACKGROUND: Epidemiological studies show that maternal diabetes predisposes offspring to cardiovascular and metabolic disorders. However, the precise mechanisms for the underlying penetrance and disease predisposition remain poorly understood. We examined whether hypoxia-inducible factor 1 alpha, in...
Autores principales: | Cerychova, Radka, Bohuslavova, Romana, Papousek, Frantisek, Sedmera, David, Abaffy, Pavel, Benes, Vladimir, Kolar, Frantisek, Pavlinkova, Gabriela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948854/ https://www.ncbi.nlm.nih.gov/pubmed/29753320 http://dx.doi.org/10.1186/s12933-018-0713-0 |
Ejemplares similares
-
HIF-1α is required for development of the sympathetic nervous system
por: Bohuslavova, Romana, et al.
Publicado: (2019) -
Dysregulation of hypoxia-inducible factor 1α in the sympathetic nervous system accelerates diabetic cardiomyopathy
por: Hrabalova, Petra, et al.
Publicado: (2023) -
Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice
por: Bohuslavova, Romana, et al.
Publicado: (2014) -
HIF-1, Metabolism, and Diabetes in the Embryonic and Adult Heart
por: Cerychova, Radka, et al.
Publicado: (2018) -
Renal injury is accelerated by global hypoxia-inducible factor 1 alpha deficiency in a mouse model of STZ-induced diabetes
por: Bohuslavova, Romana, et al.
Publicado: (2017)