Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer

TIGAR is a p53 target gene that is known to protect cells from ROS-induced apoptosis by promoting the pentose phosphate pathway. The role of TIGAR in tumor cell invasion and metastasis remains elusive. Here we found that downregulation of TIGAR reduced the invasion and metastasis of NSCLC cells in v...

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Detalles Bibliográficos
Autores principales: Shen, Mengqin, Zhao, Xiaoping, Zhao, Li, Shi, Liang, An, Shuxian, Huang, Gang, Liu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948872/
https://www.ncbi.nlm.nih.gov/pubmed/29753331
http://dx.doi.org/10.1186/s12943-018-0839-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948872/
https://www.ncbi.nlm.nih.gov/pubmed/29753331
http://dx.doi.org/10.1186/s12943-018-0839-4

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