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High-efficiency derivation of human embryonic stem cell lines using a culture system with minimized trophoblast cell proliferation

BACKGROUND: Due to their extensive self-renewal and multilineage differentiation capacity, human embryonic stem cells (hESCs) have great potential for studying developmental biology, disease modeling, and developing cell replacement therapy. The first hESC line was generated in 1998 by culturing inn...

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Detalles Bibliográficos
Autores principales: Laowtammathron, Chuti, Chingsuwanrote, Pimjai, Choavaratana, Roungsin, Phornwilardsiri, Suphadtra, Sitthirit, Ketsara, Kaewjunun, Chidchanok, Makemaharn, Orawan, Terbto, Papussorn, Waeteekul, Supaporn, Lorthongpanich, Chanchao, U-pratya, Yaowalak, Srisook, Pimonwan, Kheolamai, Pakpoom, Issaragrisil, Surapol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948903/
https://www.ncbi.nlm.nih.gov/pubmed/29751777
http://dx.doi.org/10.1186/s13287-018-0866-5