Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) can influence patient outcome such as drug response and toxicity after drug intervention. The purpose of this study is to develop a systematic pathway approach to accurately and efficiently predict novel non-synonymous SNPs (nsSNPs) that could be ca...

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Detalles Bibliográficos
Autores principales: Limviphuvadh, Vachiranee, Tan, Chee Seng, Konishi, Fumikazu, Jenjaroenpun, Piroon, Xiang, Joy Shengnan, Kremenska, Yuliya, Mu, Yar Soe, Syn, Nicholas, Lee, Soo Chin, Soo, Ross A., Eisenhaber, Frank, Maurer-Stroh, Sebastian, Yong, Wei Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948914/
https://www.ncbi.nlm.nih.gov/pubmed/29751792
http://dx.doi.org/10.1186/s12885-018-4471-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948914/
https://www.ncbi.nlm.nih.gov/pubmed/29751792
http://dx.doi.org/10.1186/s12885-018-4471-x

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