Cargando…

Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) can influence patient outcome such as drug response and toxicity after drug intervention. The purpose of this study is to develop a systematic pathway approach to accurately and efficiently predict novel non-synonymous SNPs (nsSNPs) that could be ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Limviphuvadh, Vachiranee, Tan, Chee Seng, Konishi, Fumikazu, Jenjaroenpun, Piroon, Xiang, Joy Shengnan, Kremenska, Yuliya, Mu, Yar Soe, Syn, Nicholas, Lee, Soo Chin, Soo, Ross A., Eisenhaber, Frank, Maurer-Stroh, Sebastian, Yong, Wei Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948914/ https://www.ncbi.nlm.nih.gov/pubmed/29751792 http://dx.doi.org/10.1186/s12885-018-4471-x

Ejemplares similares

Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2
por: Limviphuvadh, Vachiranee, et al.
Publicado: (2010)

AllerCatPro—prediction of protein allergenicity potential from the protein sequence
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2019)

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing
por: Jenjaroenpun, Piroon, et al.
Publicado: (2013)

AllerCatPro 2.0: a web server for predicting protein allergenicity potential
por: Nguyen, Minh N, et al.
Publicado: (2022)

Novel SNP improves differential survivability and mortality in non-small cell lung cancer patients
por: Mah, Tzia Liang, et al.
Publicado: (2014)

Application of AllerCatPro 2.0 for protein safety assessments of consumer products
por: Krutz, Nora L., et al.
Publicado: (2023)

Happiness, wellbeing and society: what matters for Singaporeans
por: Tambyah, Siok Kuan, et al.
Publicado: (2018)

Gluconobacter dominates the gut microbiome of the Asian palm civet Paradoxurus hermaphroditus that produces kopi luwak
por: Watanabe, Hikaru, et al.
Publicado: (2020)

Refinement and prediction of protein prenylation motifs
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2005)

On the necessity of dissecting sequence similarity scores into segment-specific contributions for inferring protein homology, function prediction and annotation
por: Wong, Wing-Cheong, et al.
Publicado: (2014)

Single‐residue posttranslational modification sites at the N‐terminus, C‐terminus or in‐between: To be or not to be exposed for enzyme access
por: Sirota, Fernanda L., et al.
Publicado: (2015)

Protein prenyltransferases
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2003)

Patterns of Daily Outdoor Light Exposure in Australian and Singaporean Children
por: Read, Scott A., et al.
Publicado: (2018)

A Web Server for GPCR-GPCR Interaction Pair Prediction
por: Nemoto, Wataru, et al.
Publicado: (2022)

Corrigendum: A Web Server for GPCR-GPCR Interaction Pair Prediction
por: Nemoto, Wataru, et al.
Publicado: (2022)

Functional Classification of Super-Large Families of Enzymes Based on Substrate Binding Pocket Residues for Biocatalysis and Enzyme Engineering Applications
por: Sirota, Fernanda L., et al.
Publicado: (2021)

Not all transmembrane helices are born equal: Towards the extension of the sequence homology concept to membrane proteins
por: Wong, Wing-Cheong, et al.
Publicado: (2011)

More Than 1,001 Problems with Protein Domain Databases: Transmembrane Regions, Signal Peptides and the Issue of Sequence Homology
por: Wong, Wing-Cheong, et al.
Publicado: (2010)

Discovering candidate SNPs for resilience breeding of red clover
por: Osterman, Johanna, et al.
Publicado: (2022)

BMI and Diabetes Risk in Singaporean Chinese
por: Odegaard, Andrew O., et al.
Publicado: (2009)

Cashew nut allergy in Singaporean children
por: Chitta, Spurthi, et al.
Publicado: (2018)

TTS Mapping: integrative WEB tool for analysis of triplex formation target DNA Sequences, G-quadruplets and non-protein coding regulatory DNA elements in the human genome
por: Jenjaroenpun, Piroon, et al.
Publicado: (2009)

Transmembrane helix: simple or complex
por: Wong, Wing-Cheong, et al.
Publicado: (2012)

The highly pathogenic H7N3 avian influenza strain from July 2012 in Mexico acquired an extended cleavage site through recombination with host 28S rRNA
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2013)

Predictors of screen viewing time in young Singaporean children: the GUSTO cohort
por: Bernard, Jonathan Y., et al.
Publicado: (2017)

Annual Myopia Progression and Subsequent 2-Year Myopia Progression in Singaporean Children
por: Matsumura, Saiko, et al.
Publicado: (2020)

Singaporean Mothers’ Perception of Their Three-year-old Child’s Weight Status: A Cross-Sectional Study
por: Cheng, Tuck Seng, et al.
Publicado: (2016)

Wholegrain Food Acceptance in Young Singaporean Adults
por: Neo, Jia En, et al.
Publicado: (2017)

Discovering Genome-Wide Tag SNPs Based on the Mutual Information of the Variants
por: Elmas, Abdulkadir, et al.
Publicado: (2016)

How bioinformatics influences health informatics: usage of biomolecular sequences, expression profiles and automated microscopic image analyses for clinical needs and public health
por: Kuznetsov, Vladimir, et al.
Publicado: (2013)

Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo
por: Benetka, Wolfgang, et al.
Publicado: (2006)

A qualitative study on Singaporean women’s views towards breast cancer screening and Single Nucleotide Polymorphisms (SNPs) gene testing to guide personalised screening strategies
por: Wong, Xin Yi, et al.
Publicado: (2017)

Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients
por: Chan, Sze Ling, et al.
Publicado: (2017)

Statistics of protein-DNA binding and the total number of binding sites for a transcription factor in the mammalian genome
por: Kuznetsov, Vladimir A, et al.
Publicado: (2010)

Difference in Striae Periodicity of Heilongjiang and Singaporean Chinese Teeth
por: Tan, Sharon H. X., et al.
Publicado: (2017)

Social Network Types and Health Among Older Singaporeans
por: Malhotra, Rahul, et al.
Publicado: (2020)

Socio-demographic and maternal predictors of adherence to 24-hour movement guidelines in Singaporean children
por: Chen, Bozhi, et al.
Publicado: (2019)

Native RNA or cDNA Sequencing for Transcriptomic Analysis: A Case Study on Saccharomyces cerevisiae
por: Wongsurawat, Thidathip, et al.
Publicado: (2022)

Towards Complete Sets of Farnesylated and Geranylgeranylated Proteins
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2007)

Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites
por: Maurer-Stroh, Sebastian, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_9bgravh0csf26ucfuc4iiae6bo