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Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor

The acute phase of spinal cord injury is characterized by excitotoxic and inflammatory events that mediate extensive neuronal loss in the gray matter. Neural crest stem cells (NCSCs) can exert neuroprotective and anti-inflammatory effects that may be mediated by soluble factors. We therefore hypothe...

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Detalles Bibliográficos
Autores principales: Schizas, Nikos, König, N., Andersson, B., Vasylovska, S., Hoeber, J., Kozlova, E. N., Hailer, N. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949140/
https://www.ncbi.nlm.nih.gov/pubmed/29516218
http://dx.doi.org/10.1007/s00441-018-2808-z