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Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in a mouse model of acute myocardial infarction

Ischemic heart disease (IHD) is a leading cause of morbidity and mortality worldwide. Growth hormone secretagogues (GHS) have been shown to improve cardiac function in models of IHD. This study determined whether hexarelin (HEX), a synthetic GHS, preserves cardiac function and morphology in a mouse...

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Detalles Bibliográficos
Autores principales: McDonald, Hayley, Peart, Jason, Kurniawan, Nyoman, Galloway, Graham, Royce, Simon, Samuel, Chrishan S., Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949285/
https://www.ncbi.nlm.nih.gov/pubmed/29756411
http://dx.doi.org/10.14814/phy2.13699