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MAD1: Kinetochore Receptors and Catalytic Mechanisms

The mitotic checkpoint monitors kinetochore-microtubule attachment, delays anaphase onset and prevents aneuploidy when unattached or tensionless kinetochores are present in cells. Mitotic arrest deficiency 1 (MAD1) is one of the evolutionarily conserved core mitotic checkpoint proteins. MAD1 forms a...

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Detalles Bibliográficos
Autores principales: Luo, Yibo, Ahmad, Ejaz, Liu, Song-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949338/
https://www.ncbi.nlm.nih.gov/pubmed/29868582
http://dx.doi.org/10.3389/fcell.2018.00051