Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice

After spinal cord injury (SCI), reconstruction of neuronal tracts is very difficult because an inhibitory scar is formed at the lesion site, in which several axonal growth inhibitors, such as chondroitin sulfate proteoglycans (CSPG), accumulate. We previously found that matrine, a major alkaloid in...

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Detalles Bibliográficos
Autores principales: Tanabe, Norio, Kuboyama, Tomoharu, Tohda, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949560/
https://www.ncbi.nlm.nih.gov/pubmed/29867458
http://dx.doi.org/10.3389/fphar.2018.00446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949560/
https://www.ncbi.nlm.nih.gov/pubmed/29867458
http://dx.doi.org/10.3389/fphar.2018.00446

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