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Telmisartan reverses antiretroviral-induced adipocyte toxicity and insulin resistance in vitro

BACKGROUND: Antiretroviral therapy in HIV-positive patients leads to insulin resistance which is central to the pathogenesis of various metabolic abnormalities and cardiovascular disease seen in this patient group. We have investigated the dose–response relationship of telmisartan, an antihypertensi...

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Detalles Bibliográficos
Autores principales: Pushpakom, Sudeep P, Adaikalakoteswari, Antonysunil, Owen, Andrew, Back, David J, Tripathi, Gyanendra, Kumar, Sudhesh, McTernan, Philip, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949706/
https://www.ncbi.nlm.nih.gov/pubmed/29466880
http://dx.doi.org/10.1177/1479164118757924