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Advances and Challenges on Management of Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) originate from interstitial cells of Cajal and account for over 5,000 newly diagnosed cases in the United States. The discovery of activated KIT and PDGFRA mutations and introduction of imatinib revolutionized the treatment strategy and opened up the new era o...

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Detalles Bibliográficos
Autores principales: Mei, Lin, Du, Wei, Idowu, Michael, von Mehren, Margaret, Boikos, Sosipatros A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949718/
https://www.ncbi.nlm.nih.gov/pubmed/29868467
http://dx.doi.org/10.3389/fonc.2018.00135