In vivo demonstration of an active tumor pretargeting approach with peptide nucleic acid bioconjugates as complementary system

A novel, promising strategy for cancer diagnosis and therapy is the use of a pretargeting approach. For this purpose, the non-natural DNA/RNA analogues Peptide Nucleic Acids (PNAs) are ideal candidates as in vivo recognition units due to their high metabolic stability and lack of unspecific accumula...

Descripción completa

Detalles Bibliográficos
Autores principales: Leonidova, Anna, Foerster, Christian, Zarschler, Kristof, Schubert, Maik, Pietzsch, Hans-Jürgen, Steinbach, Jörg, Bergmann, Ralf, Metzler-Nolte, Nils, Stephan, Holger, Gasser, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949856/
https://www.ncbi.nlm.nih.gov/pubmed/29861898
http://dx.doi.org/10.1039/c5sc00951k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949856/
https://www.ncbi.nlm.nih.gov/pubmed/29861898
http://dx.doi.org/10.1039/c5sc00951k

Ejemplares similares