High‐throughput discovery of functional disordered regions: investigation of transactivation domains

Over 40% of proteins in any eukaryotic genome encode intrinsically disordered regions (IDRs) that do not adopt defined tertiary structures. Certain IDRs perform critical functions, but discovering them is non‐trivial as the biological context determines their function. We present IDR‐Screen, a frame...

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Detalles Bibliográficos
Autores principales: Ravarani, Charles NJ, Erkina, Tamara Y, De Baets, Greet, Dudman, Daniel C, Erkine, Alexandre M, Babu, M Madan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949888/
https://www.ncbi.nlm.nih.gov/pubmed/29759983
http://dx.doi.org/10.15252/msb.20188190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949888/
https://www.ncbi.nlm.nih.gov/pubmed/29759983
http://dx.doi.org/10.15252/msb.20188190

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