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Asiatic acid inhibits proliferation, migration and induces apoptosis by regulating Pdcd4 via the PI3K/Akt/mTOR/p70S6K signaling pathway in human colon carcinoma cells

Previous studies have demonstrated that asiatic acid (AA), the major component of Centella asiatica, is able to meditate cytotoxic and anticancer effects on various types of carcinoma cells. In order to investigate the molecular mechanism that underlies the antitumor effect of AA, the present study...

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Detalles Bibliográficos
Autores principales: Hao, Yajuan, Huang, Jiawei, Ma, Yun, Chen, Wancheng, Fan, Qin, Sun, Xuegang, Shao, Meng, Cai, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950025/
https://www.ncbi.nlm.nih.gov/pubmed/29805556
http://dx.doi.org/10.3892/ol.2018.8417