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CHAT gene polymorphism rs3810950 is associated with the risk of Alzheimer’s disease in the Czech population

BACKGROUND: Cholinergic hypothesis of Alzheimer’s disease (AD) is based on the findings that a reduced and/or perturbed cholinergic activity in the central nervous system correlates with cognitive decline in patients with Alzheimer’s disease. The hypothesis resulted in the development of centrally-a...

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Detalles Bibliográficos
Autores principales: Hálová, Alice, Janoutová, Jana, Ewerlingová, Laura, Janout, Vladimír, Bonczek, Ondřej, Zeman, Tomáš, Gerguri, Tereza, Balcar, Vladimir J., Šerý, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950140/
https://www.ncbi.nlm.nih.gov/pubmed/29759072
http://dx.doi.org/10.1186/s12929-018-0444-2