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CHAT gene polymorphism rs3810950 is associated with the risk of Alzheimer’s disease in the Czech population
BACKGROUND: Cholinergic hypothesis of Alzheimer’s disease (AD) is based on the findings that a reduced and/or perturbed cholinergic activity in the central nervous system correlates with cognitive decline in patients with Alzheimer’s disease. The hypothesis resulted in the development of centrally-a...
Autores principales: | Hálová, Alice, Janoutová, Jana, Ewerlingová, Laura, Janout, Vladimír, Bonczek, Ondřej, Zeman, Tomáš, Gerguri, Tereza, Balcar, Vladimir J., Šerý, Omar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950140/ https://www.ncbi.nlm.nih.gov/pubmed/29759072 http://dx.doi.org/10.1186/s12929-018-0444-2 |
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