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Hypermethylation of protocadherin γ subfamily A12 and solute carrier family 19 A 1 promoters contributes to the occurrence and metastasis of colorectal cancer

The development of colorectal cancer (CRC) involves genetic and epigenetic modifications, and aberrant DNA methylation within gene promoters is a primary mediator of epigenetic inheritance in CRC. The present study evaluated whether promoter methylation of four CRC candidate genes [protocadherin γ s...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Li, Jinyun, Huang, Tao, Chen, Cheng, Hong, Qingxiao, Ji, Huihui, Ye, Meng, Duan, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950180/
https://www.ncbi.nlm.nih.gov/pubmed/29805555
http://dx.doi.org/10.3892/ol.2018.8393