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Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer

E2F4 is an important basal transcription factor with the potential to promote tumor growth. Its upregulation in various types of cancer has been linked to numerous genetic factors; however, the nature of the involvement of epigenetic mechanisms, including DNA methylation, remains elusive. In the pre...

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Detalles Bibliográficos
Autores principales: Farman, Farman Ullah, Haq, Farhan, Muhammad, Noor, Ali, Nawab, Rahman, Hazir, Saeed, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950537/
https://www.ncbi.nlm.nih.gov/pubmed/29805583
http://dx.doi.org/10.3892/ol.2018.8382