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Aberrant promoter methylation status is associated with upregulation of the E2F4 gene in breast cancer
E2F4 is an important basal transcription factor with the potential to promote tumor growth. Its upregulation in various types of cancer has been linked to numerous genetic factors; however, the nature of the involvement of epigenetic mechanisms, including DNA methylation, remains elusive. In the pre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950537/ https://www.ncbi.nlm.nih.gov/pubmed/29805583 http://dx.doi.org/10.3892/ol.2018.8382 |