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Induced dural lymphangiogenesis facilities soluble amyloid-beta clearance from brain in a transgenic mouse model of Alzheimer's disease

Impaired amyloid-β clearance from the brain is a core pathological event in Alzheimer's disease. The therapeutic effect of current pharmacotherapies is unsatisfactory, and some treatments cause severe side effects. The meningeal lymphatic vessels might be a new route for amyloid-β clearance. Th...

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Detalles Bibliográficos
Autores principales: Wen, Ya-Ru, Yang, Jun-Hua, Wang, Xiao, Yao, Zhi-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950683/
https://www.ncbi.nlm.nih.gov/pubmed/29722325
http://dx.doi.org/10.4103/1673-5374.230299