Cargando…

Induced dural lymphangiogenesis facilities soluble amyloid-beta clearance from brain in a transgenic mouse model of Alzheimer's disease

Impaired amyloid-β clearance from the brain is a core pathological event in Alzheimer's disease. The therapeutic effect of current pharmacotherapies is unsatisfactory, and some treatments cause severe side effects. The meningeal lymphatic vessels might be a new route for amyloid-β clearance. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Ya-Ru, Yang, Jun-Hua, Wang, Xiao, Yao, Zhi-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950683/ https://www.ncbi.nlm.nih.gov/pubmed/29722325 http://dx.doi.org/10.4103/1673-5374.230299

Ejemplares similares

Choroid plexus dysfunction impairs beta-amyloid clearance in a triple transgenic mouse model of Alzheimer’s disease
por: González-Marrero, Ibrahim, et al.
Publicado: (2015)

Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta Clearance
por: Malm, Tarja, et al.
Publicado: (2012)

Editorial on, “Amyloid-beta clearance in Alzheimer's disease”
por: Marr, Robert A.
Publicado: (2014)

Amyloid-beta and Alzheimer’s disease: the role of neprilysin-2 in amyloid-beta clearance
por: Marr, Robert A., et al.
Publicado: (2014)

Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model
por: Freitag, Kiara, et al.
Publicado: (2022)

Night Photostimulation of Clearance of Beta-Amyloid from Mouse Brain: New Strategies in Preventing Alzheimer’s Disease
por: Semyachkina-Glushkovskaya, Oxana, et al.
Publicado: (2021)

Ergothioneine, a dietary antioxidant improves amyloid beta clearance in the neuroretina of a mouse model of Alzheimer’s disease
por: Wijesinghe, Printha, et al.
Publicado: (2023)

Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease
por: Xiang, Yang, et al.
Publicado: (2015)

Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease
por: Lee, Jiyeon, et al.
Publicado: (2019)

Water influx into cerebrospinal fluid is significantly reduced in senile plaque bearing transgenic mice, supporting beta-amyloid clearance hypothesis of Alzheimer’s disease
por: Igarashi, Hironaka, et al.
Publicado: (2014)

Soluble Amyloid-beta Aggregates from Human Alzheimer’s Disease Brains
por: Esparza, Thomas J., et al.
Publicado: (2016)

Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology
por: Povala, Guilherme, et al.
Publicado: (2021)

Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance
por: Feng, Weixi, et al.
Publicado: (2020)

Heat Shock Proteins and Amateur Chaperones in Amyloid-Beta Accumulation and Clearance in Alzheimer’s Disease
por: Wilhelmus, Micha M. M., et al.
Publicado: (2007)

Intranasal Delivery of Collagen-Loaded Neprilysin Clears Beta-Amyloid Plaques in a Transgenic Alzheimer Mouse Model
por: Humpel, Christian
Publicado: (2021)

Electroacupuncture Improves Clearance of Amyloid-β through the Glymphatic System in the SAMP8 Mouse Model of Alzheimer's Disease
por: Liang, Pei-zhe, et al.
Publicado: (2021)

Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer’s disease
por: Ali, Tahir, et al.
Publicado: (2023)

The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease
por: ElAli, Ayman, et al.
Publicado: (2013)

Parasagittal dural space hypertrophy and amyloid-β deposition in Alzheimer’s disease
por: Song, Alexander K, et al.
Publicado: (2023)

Intravenous Infusion of Monocytes Isolated from 2-Week-Old Mice Enhances Clearance of Beta-Amyloid Plaques in an Alzheimer Mouse Model
por: Hohsfield, Lindsay A., et al.
Publicado: (2015)

Anticoagulants inhibit proteolytic clearance of plasma amyloid beta
por: Yang, Lu, et al.
Publicado: (2017)

Patients with Alzheimer’s disease have an increased removal rate of soluble beta-amyloid-42
por: Zaretsky, Dmitry V., et al.
Publicado: (2022)

Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease
por: Subash, Selvaraju, et al.
Publicado: (2015)

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimer’s Disease via Decreasing Beta-Amyloid Production and Tau Hyperphosphorylation
por: Bao, Xiu-Qi, et al.
Publicado: (2013)

Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer’s disease mouse model
por: Kim, Shin Heun, et al.
Publicado: (2020)

Transgenic tomatoes expressing human beta-amyloid for use as a vaccine against Alzheimer’s disease
por: Youm, Jung Won, et al.
Publicado: (2008)

Evidence for impaired amyloid β clearance in Alzheimer's disease
por: Wildsmith, Kristin R, et al.
Publicado: (2013)

Increased tauopathy drives microglia-mediated clearance of beta-amyloid
por: Chen, Wesley, et al.
Publicado: (2016)

Clearance of amyloid‐beta with bispecific antibody constructs bound to erythrocytes
por: Taylor, Ronald P., et al.
Publicado: (2020)

Microglial amyloid beta clearance is driven by PIEZO1 channels
por: Jäntti, Henna, et al.
Publicado: (2022)

Scara1 deficiency impairs clearance of soluble Amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression
por: Frenkel, Dan, et al.
Publicado: (2013)

The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets
por: Qi, Xue-mei, et al.
Publicado: (2017)

Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls
por: Esparza, Thomas J., et al.
Publicado: (2018)

Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
por: Sideris, Dimitrios I, et al.
Publicado: (2021)

Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: the role, regulation and restoration of LRP1
por: Ramanathan, Anita, et al.
Publicado: (2015)

NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease
por: He, Xiao-fei, et al.
Publicado: (2020)

Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer’s mouse model
por: Yuede, Carla M., et al.
Publicado: (2016)

A transgenic Xenopus laevis reporter model to study lymphangiogenesis
por: Ny, Annelii, et al.
Publicado: (2013)

Effect of Bacterial Amyloid Protein Phenol−Soluble Modulin Alpha 3 on the Aggregation of Amyloid Beta Protein Associated with Alzheimer’s Disease
por: Peng, Bushu, et al.
Publicado: (2023)

Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy
por: Fella, Eleni, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s00pe14pgrkdr4h41d3rmabr7b