Cargando…

Downregulation of MiR-199b-5p Inducing Differentiation of Bone-Marrow Mesenchymal Stem Cells (BMSCs) Toward Cardiomyocyte-Like Cells via HSF1/HSP70 Pathway

BACKGROUND: Bone-marrow mesenchymal stem cells (BMSCs) are pluripotent stem cells with potent self-renewal and differentiation ability that are widely used in transplantation of cell therapy. But the mechanism on microRNA (miRNA) regulating stem cell differentiation is complicated and unclear. The a...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Fangjie, Du, Peizhao, Chang, Yaowei, Ji, Endong, Xu, Yunjia, Wei, Chunyan, Li, Jiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951024/
https://www.ncbi.nlm.nih.gov/pubmed/29715263
http://dx.doi.org/10.12659/MSM.907441