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Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells

INTRODUCTION: Prostate cancer is the most common noncutaneous cancer and the second leading cause of cancer-related mortality worldwide and the third in USA in 2017. Chelerythrine (CHE), a naturalbenzo[c]phenanthridine alkaloid, formerly identified as a protein kinase C inhibitor, has also shown ant...

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Detalles Bibliográficos
Autores principales: Wu, Songjiang, Yang, Yanying, Li, Feiping, Huang, Lifu, Han, Zihua, Wang, Guanfu, Yu, Hongyuan, Li, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951218/
https://www.ncbi.nlm.nih.gov/pubmed/29780252
http://dx.doi.org/10.2147/OTT.S157707