Cargando…

Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells

INTRODUCTION: Prostate cancer is the most common noncutaneous cancer and the second leading cause of cancer-related mortality worldwide and the third in USA in 2017. Chelerythrine (CHE), a naturalbenzo[c]phenanthridine alkaloid, formerly identified as a protein kinase C inhibitor, has also shown ant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Songjiang, Yang, Yanying, Li, Feiping, Huang, Lifu, Han, Zihua, Wang, Guanfu, Yu, Hongyuan, Li, Haiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951218/ https://www.ncbi.nlm.nih.gov/pubmed/29780252 http://dx.doi.org/10.2147/OTT.S157707

Ejemplares similares

Chelerythrine induces apoptosis via ROS‐mediated endoplasmic reticulum stress and STAT3 pathways in human renal cell carcinoma
por: He, Hongchao, et al.
Publicado: (2019)

Nodakenin Induces ROS-Dependent Apoptotic Cell Death and ER Stress in Radioresistant Breast Cancer
por: Kim, Tae Woo
Publicado: (2023)

Curcumin analog WZ35 induced cell death via ROS-dependent ER stress and G2/M cell cycle arrest in human prostate cancer cells
por: Zhang, Xiuhua, et al.
Publicado: (2015)

Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway
por: Lin, Yanling, et al.
Publicado: (2022)

Extraction of Chelerythrine and its Effects on Pathogenic Fungus Spore Germination
por: Wei, Qinghui, et al.
Publicado: (2017)

Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes
por: Bai, Li-Ping, et al.
Publicado: (2014)

A method for reducing thermal injury during the ureteroscopic holmium laser lithotripsy
por: Zhu, Xiaoliang, et al.
Publicado: (2023)

Autophagy Protects against Oxaliplatin-Induced Cell Death via ER Stress and ROS in Caco-2 Cells
por: Shi, Yan, et al.
Publicado: (2012)

Isoalantolactone induces apoptosis through ROS-mediated ER stress and inhibition of STAT3 in prostate cancer cells
por: Chen, Wei, et al.
Publicado: (2018)

Chelerythrine chloride induces apoptosis in renal cancer HEK-293 and SW-839 cell lines
por: CHEN, XIAO-MENG, et al.
Publicado: (2016)

Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma
por: Xu, Zhongren, et al.
Publicado: (2022)

Rediscovery of Traditional Plant Medicine: An Underestimated Anticancer Drug of Chelerythrine
por: Chen, Nianzhi, et al.
Publicado: (2022)

Synergistic Activity of Econazole-Nitrate and Chelerythrine against Clinical Isolates of Candida albicans
por: Chen, Zhibao, et al.
Publicado: (2014)

Disulfiram (Antabuse) Activates ROS-Dependent ER Stress and Apoptosis in Oral Cavity Squamous Cell Carcinoma
por: Shah O’Brien, Priyanka, et al.
Publicado: (2019)

In Vitro Antifungal Activity of Sanguinarine and Chelerythrine Derivatives against Phytopathogenic Fungi
por: Yang, Xin-Juan, et al.
Publicado: (2012)

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis
por: Ghashghaeinia, Mehrdad, et al.
Publicado: (2020)

MicroRNA-143-3p/TBX3 Axis Represses Malignant Cell Behaviors in Bladder Cancer
por: Huang, Lifu, et al.
Publicado: (2022)

Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells
por: Tang, Zheng-Hai, et al.
Publicado: (2017)

Chelerythrine Chloride Downregulates β-Catenin and Inhibits Stem Cell Properties of Non-Small Cell Lung Carcinoma
por: Heng, Win Sen, et al.
Publicado: (2020)

Shikonin Induces ROS-Dependent Apoptosis Via Mitochondria Depolarization and ER Stress in Adult T Cell Leukemia/Lymphoma
por: Boonnate, Piyanard, et al.
Publicado: (2023)

Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells
por: Lin, Wanjun, et al.
Publicado: (2017)

Involvement of ER stress in retinal cell death
por: Shimazawa, Masamitsu, et al.
Publicado: (2007)

EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells
por: Sagar, Vinay, et al.
Publicado: (2019)

Using Liposomes to Alleviate the Toxicity of Chelerythrine, a Natural PKC Inhibitor, in Treating Non-Small Cell Lung Cancer
por: Wang, Jiahui, et al.
Publicado: (2021)

Antibacterial mechanism of chelerythrine isolated from root of Toddalia asiatica (Linn) Lam
por: He, Nan, et al.
Publicado: (2018)

Therapeutic potential of chelerythrine as a multi-purpose adjuvant for the treatment of COVID-19
por: Valipour, Mehdi, et al.
Publicado: (2021)

Chelerythrine Chloride: A Potential Rumen Microbial Urease Inhibitor Screened by Targeting UreG
por: Zhang, Xiaoyin, et al.
Publicado: (2021)

Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux
por: Yang, Dong-lin, et al.
Publicado: (2021)

Role of ER Stress Response in Photodynamic Therapy: ROS Generated in Different Subcellular Compartments Trigger Diverse Cell Death Pathways
por: Moserova, Irena, et al.
Publicado: (2012)

Relationship of oestrogen receptor alpha gene polymorphisms with risk for benign prostatic hyperplasia and prostate cancer in Chinese men
por: Han, Zihua, et al.
Publicado: (2017)

Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells
por: Ma, Jun, et al.
Publicado: (2015)

ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells
por: Celesia, Adriana, et al.
Publicado: (2020)

Fluorescence, Absorption, Chromatography and Structural Transformation of Chelerythrine and Ethoxychelerythrine in Protic Solvents: A Comparative Study
por: Cao, Jinjin, et al.
Publicado: (2022)

HO-3867 Induces ROS-Dependent Stress Response and Apoptotic Cell Death in Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2021)

TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole
por: Oberstadt, Moritz, et al.
Publicado: (2018)

Chelerythrine Inhibits Stemness of Cancer Stem-Like Cells of Osteosarcoma and PI3K/AKT/mTOR Signal
por: Chen, Zhixing, et al.
Publicado: (2022)

Echinacoside inhibited cardiomyocyte pyroptosis and improved heart function of HF rats induced by isoproterenol via suppressing NADPH/ROS/ER stress
por: Ni, YaJuan, et al.
Publicado: (2022)

Trichomonas vaginalis induces apoptosis via ROS and ER stress response through ER–mitochondria crosstalk in SiHa cells
por: Gao, Fei Fei, et al.
Publicado: (2021)

Quercetin Enhanced Paclitaxel Therapeutic Effects Towards PC-3 Prostate Cancer Through ER Stress Induction and ROS Production
por: Zhang, Xiangyu, et al.
Publicado: (2020)

Camalexin Induces Apoptosis via the ROS-ER Stress-Mitochondrial Apoptosis Pathway in AML Cells
por: Yang, Yang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a3bv345ecmdcbmulgivnlnghkn