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WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling

BACKGROUND: Though we recently reported that the WWC3 inhibits the invasiveness and metastasis of lung cancer by activating the Hippo pathway, the impact and underlying mechanisms of this process still remain unclear. METHODS: To identify the role of WWC3 in epithelial-mesenchymal transition of lung...

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Detalles Bibliográficos
Autores principales: Han, Qiang, Kremerskothen, Joachim, Lin, Xuyong, Zhang, Xiupeng, Rong, Xuezhu, Zhang, Di, Wang, Enhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951220/
https://www.ncbi.nlm.nih.gov/pubmed/29780251
http://dx.doi.org/10.2147/OTT.S162387