The SMAD2/3 interactome reveals that TGFβ controls m(6)A mRNA methylation in pluripotency

The TGFβ pathway plays an essential role in embryonic development, organ homeostasis, tissue repair, and disease1,2. This diversity of tasks is achieved through the intracellular effector SMAD2/3, whose canonical function is to control activity of target genes by interacting with transcriptional reg...

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Detalles Bibliográficos
Autores principales: Bertero, Alessandro, Brown, Stephanie, Madrigal, Pedro, Osnato, Anna, Ortmann, Daniel, Yiangou, Loukia, Kadiwala, Juned, Hubner, Nina C., de los Mozos, Igor Ruiz, Sadee, Christoph, Lenaerts, An-Sofie, Nakanoh, Shota, Grandy, Rodrigo, Farnell, Edward, Ule, Jernej, Stunnenberg, Hendrik G., Mendjan, Sasha, Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951268/
https://www.ncbi.nlm.nih.gov/pubmed/29489750
http://dx.doi.org/10.1038/nature25784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951268/
https://www.ncbi.nlm.nih.gov/pubmed/29489750
http://dx.doi.org/10.1038/nature25784

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