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Effects of palonosetron for prophylaxis of postoperative nausea and vomiting in high-risk patients undergoing total knee arthroplasty: A prospective, randomized, double-blind, placebo-controlled study

BACKGROUND: The preemptive multimodal pain protocols used in total knee arthroplasty (TKA) often cause emesis postoperatively. We investigated whether palonosetron prophylaxis reduces postoperative nausea and vomiting (PONV) in high-risk patients after TKA. METHODS: We randomized 120 female patients...

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Detalles Bibliográficos
Autores principales: Ryu, Jung-Hee, Jeon, Young-Tae, Min, Byunghun, Hwang, Jin-Young, Sohn, Hye-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951557/
https://www.ncbi.nlm.nih.gov/pubmed/29758039
http://dx.doi.org/10.1371/journal.pone.0196388