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CLCA2 is a positive regulator of store-operated calcium entry and TMEM16A

The Chloride Channel Accessory (CLCA) protein family was first characterized as regulators of calcium-activated chloride channel (CaCC) currents (I(CaCC)), but the mechanism has not been fully established. We hypothesized that CLCAs might regulate I(CaCC) by modulating intracellular calcium levels....

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Detalles Bibliográficos
Autores principales: Sharma, Aarushi, Ramena, Grace, Yin, Yufang, Premkumar, Louis, Elble, Randolph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951673/
https://www.ncbi.nlm.nih.gov/pubmed/29758025
http://dx.doi.org/10.1371/journal.pone.0196512