Electron cryo-microscopy structure of the canonical TRPC4 ion channel

Canonical transient receptor channels (TRPC) are non-selective cation channels. They are involved in receptor-operated Ca(2+) signaling and have been proposed to act as store-operated channels (SOC). Their malfunction is related to cardiomyopathies and their modulation by small molecules has been sh...

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Detalles Bibliográficos
Autores principales: Vinayagam, Deivanayagabarathy, Mager, Thomas, Apelbaum, Amir, Bothe, Arne, Merino, Felipe, Hofnagel, Oliver, Gatsogiannis, Christos, Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951680/
https://www.ncbi.nlm.nih.gov/pubmed/29717981
http://dx.doi.org/10.7554/eLife.36615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951680/
https://www.ncbi.nlm.nih.gov/pubmed/29717981
http://dx.doi.org/10.7554/eLife.36615

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