Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers

Colorectal cancer (CRC) accounts for about 8% of all new cancer cases diagnosed in the US. We used whole exome sequence data from triplet samples (colon carcinoma, colon adenoma, and normal tissue) from 18 individuals to assess gene mutation rates. Of the 2 204 genes that were mutated, APC, TTN, TP5...

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Detalles Bibliográficos
Autores principales: Wolff, Roger K., Hoffman, Michael D., Wolff, Erica C., Herrick, Jennifer S., Sakoda, Lori C., Samowitz, Wade S., Slattery, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951744/
https://www.ncbi.nlm.nih.gov/pubmed/29575536
http://dx.doi.org/10.1002/gcc.22539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951744/
https://www.ncbi.nlm.nih.gov/pubmed/29575536
http://dx.doi.org/10.1002/gcc.22539

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