Breast cancer associated germline structural variants harboring small noncoding RNAs impact post-transcriptional gene regulation

Copy Number Variants (CNVs) are a class of structural variations of DNA. Germline CNVs are known to confer disease susceptibility, but their role in breast cancer warrants further investigations. We hypothesized that breast cancer associated germline CNVs contribute to disease risk through gene dosa...

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Detalles Bibliográficos
Autores principales: Kumaran, Mahalakshmi, Krishnan, Preethi, Cass, Carol E., Hubaux, Roland, Lam, Wan, Yasui, Yutaka, Damaraju, Sambasivarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951800/
https://www.ncbi.nlm.nih.gov/pubmed/29760470
http://dx.doi.org/10.1038/s41598-018-25801-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951800/
https://www.ncbi.nlm.nih.gov/pubmed/29760470
http://dx.doi.org/10.1038/s41598-018-25801-1

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